SCHEMBL1126573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126536	0.85	CNR1 (0.46)	ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1
	SCHEMBL1126661	0.81	P2RY12 (0.51)	ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1
	SCHEMBL2806317	0.77	SMN1; SMN2 (0.49)	ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1
	SCHEMBL1126957	0.75	ALDH1A1 (0.50)	ALDH1A1MEN1KMT2ASMN1; SMN2POLB
	Succinic Acid Diethyl Ester SCHEMBL27940678	0.75	SMN1; SMN2 (0.62)	ALDH1A1MEN1KMT2ASMN1; SMN2POLB
	SCHEMBL15162603	0.72	GABRA2 (0.45)	GABRA2GABRB2CYP1A2CYP2C9CYP2C19
	SCHEMBL1126999	0.72	ESR1 (0.48)	ALDH1A1CREBBPSMN1; SMN2POLBLMNA
	SCHEMBL4429718	0.71	ESR1 (0.70)	ALDH1A1CREBBPMEN1KMT2ATUBB4A
	SCHEMBL1126803	0.71	ALDH1A1 (0.54)	ALDH1A1MEN1KMT2ASMN1; SMN2POLB
	SCHEMBL8379393	0.71	ALDH1A1 (0.47)	ALDH1A1SMN1; SMN2NPSR1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.