Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15219316 | 0.84 | BRD4 (0.53) | HRH3IRAK4BRD4PRKCZLCK | |
| SCHEMBL11919245 | 0.80 | BRD4 (0.46) | HRH3IRAK4BRD4PRKCZLCK | |
| SCHEMBL11916018 | 0.80 | MALT1 (0.49) | HRH3IRAK4BRD4PRKCZLCK | |
| SCHEMBL2051027 | 0.77 | PRKCZ (0.50) | IRAK4BRD4PRKCZROCK2ROCK1 | |
| SCHEMBL19477096 | 0.75 | BRD4 (0.47) | HRH3BRD4PRKCZCDK7CCNH | |
| SCHEMBL4705576 | 0.75 | IRAK4 (0.52) | IRAK4PRKCZLCKRETPDGFRB | |
| SCHEMBL15219252 | 0.74 | KDM4E (0.68) | BRD4CDK7CCNHROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL30771511 | 0.74 | PRKCZ (0.48) | IRAK4PRKCZROCK2ROCK1CDC42BPB | |
| SCHEMBL13018653 | 0.74 | HRH3 (0.83) | HRH3IRAK4BRD4FLT3IRAK1 | |
| SCHEMBL3785005 | 0.74 | HRH3 (0.83) | HRH3IRAK4BRD4FLT3IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104151312-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |