Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356685 | 0.81 | CYP19A1 (0.49) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL452340 | 0.79 | KDM4E (0.57) | PDPK1KDM4ERAB9ANPC1MAPT | |
| Fluoride SCHEMBL27903468 | 0.77 | KDM4E (0.55) | PDPK1KDM4ERAB9ANPC1MAPT | |
| Ammonia Solution, Strong SCHEMBL28442530 | 0.77 | KDM4E (0.55) | PDPK1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL752932 | 0.75 | RAB9A (0.52) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL14106734 | 0.73 | PDE10A (0.50) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL3344484 | 0.73 | KDM4E (0.46) | KDM4ERAB9ANPC1MAPTGLA | |
| Hydrochloric Acid SCHEMBL15910677 | 0.71 | PIK3CD (0.45) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL1489754 | 0.71 | KDM4E (0.50) | PDPK1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL6193707 | 0.70 | CYP2A6 (0.44) | KDM4ERAB9ANPC1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566313-A | Synthesis method of ceftaroline fosamil intermediate 4-(4'-pyridyl)-1,3-thiazolyl-2-thiol | SHAANXI SEER BIOTECHNOLOGY CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-105566313-A | Synthesis method of ceftaroline fosamil intermediate 4-(4'-pyridyl)-1,3-thiazolyl-2-thiol | SHAANXI SEER BIOTECHNOLOGY CO LTD | 2016-05-11 | — | — | CN | disclosed |