Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064040 | 0.81 | PDPK1 (0.49) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL752932 | 0.79 | RAB9A (0.52) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL14106734 | 0.76 | PDE10A (0.50) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL3344484 | 0.76 | KDM4E (0.46) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL15910677 | 0.75 | PIK3CD (0.45) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL6193707 | 0.74 | CYP2A6 (0.44) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL3344560 | 0.74 | PDE10A (0.47) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL28036411 | 0.72 | KDM4E (0.56) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL12632125 | 0.72 | PDE10A (0.42) | CYP19A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL28534899 | 0.72 | KDM4E (0.42) | CYP19A1KDM4ERAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
| EP-1367893-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002067684-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | PNPO, P2RX6, P2RX1 | CYP19A1 1268/4885KDM4E 2707/4885RAB9A 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.