Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL28064545

CC(C)(C)OC=O.O=C(N[C@@H]1CCNC[C@H]1O)OCc1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.45
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
CTSB P07858 2/20 0.42
CTSS P25774 2/20 0.42
CTSK P43235 2/20 0.42
TSHR P16473 1/20 0.42
CTSL P07711 1/20 0.42
EPHX1 P07099 1/20 0.42
SSTR1 P30872 1/20 0.40
SSTR4 P31391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butyl Formate SCHEMBL28064547 1.00 CPB1 (0.45) CPB1ALDH1A1GAAITGB3ITGA2B
SCHEMBL16683509 0.89 ALDH1A1 (0.52) CPB1ALDH1A1GAACTSBCTSS
SCHEMBL5745326 0.89 ALDH1A1 (0.52) CPB1ALDH1A1GAACTSBCTSS
Tert-Butyl Formate SCHEMBL28064433 0.89 CPB1 (0.47) CPB1ALDH1A1GAAITGB3ITGA2B
Tert-Butyl Formate SCHEMBL28064435 0.89 CPB1 (0.47) CPB1ALDH1A1GAAITGB3ITGA2B
Hydrochloric Acid SCHEMBL34467954 0.88 ALDH1A1 (0.51) CPB1ALDH1A1GAACTSBCTSS
Hydrochloric Acid SCHEMBL6582419 0.88 ALDH1A1 (0.51) CPB1ALDH1A1GAACTSBCTSS
Tert-Butyl Formate SCHEMBL28112834 0.86 ALDH1A1 (0.51) CPB1ALDH1A1GAAITGB3ITGA2B
Tert-Butyl Formate SCHEMBL28112836 0.86 ALDH1A1 (0.51) CPB1ALDH1A1GAAITGB3ITGA2B
SCHEMBL27893654 0.85 KMT2A (0.44) CPB1TSHRCTSLSSTR1SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658642-A Fibroblast growth factor receptor inhibitors 蓝图药品公司 2016-06-08 CN disclosed