Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355032 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL28796538 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL3842233 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL27879491 | 0.78 | TDP1 (0.35) | TDP1ERN1MEN1KMT2ALMNA | |
| SCHEMBL10989431 | 0.77 | TDP1 (0.43) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL23835305 | 0.75 | ERN1 (0.46) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL30151958 | 0.75 | ERN1 (0.46) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL9712540 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL14126643 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24358167 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1ERN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658642-A | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2016-06-08 | — | — | CN | disclosed |