SCHEMBL28064595

SCHEMBL28064595

CC1(C(=O)O)CC=C(CO)O1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 2/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
THPO P40225 1/20 0.31
STAT6 P42226 1/20 0.31
HIF1A Q16665 1/20 0.31
NPC1 O15118 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3166465 0.75 PTGS1 (0.37) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL23863456 0.70
SCHEMBL5736042 0.68 LMNA (0.39) PTGS2TSHRMAPK1TP53LMNA
SCHEMBL9147377 0.68 AKR1B1 (0.32) MAPK1NPC1RAB9A
SCHEMBL3971345 0.63 HPGD (0.43) NPC1RAB9ASMN1; SMN2
SCHEMBL10454155 0.60 PTGS1 (0.34) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL18204973 0.59
SCHEMBL31013390 0.58 TDP1 (0.31)
SCHEMBL335112 0.58
SCHEMBL1292326 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658700-B For generating the Compounds and methods for of nylon 6 英派尔科技开发有限公司 2018-07-10 CN disclosed
CN-105658700-A Compounds and methods for producing nylon 6 英派尔科技开发有限公司 2016-06-08 CN disclosed