Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23433032 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRDAPK1CYP2D6HDAC4 | |
| SCHEMBL1754108 | 0.79 | PDE4B (0.52) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL14353864 | 0.77 | PDE4B (0.50) | HDAC4HDAC2HDAC8HDAC6HTT | |
| SCHEMBL27490980 | 0.76 | TSHR (0.40) | SMN1; SMN2TSHRCYP2D6HTTMAPT | |
| SCHEMBL10908718 | 0.75 | HDAC4 (0.46) | SMN1; SMN2TSHRDAPK1CYP2D6HDAC4 | |
| SCHEMBL28020176 | 0.75 | HDAC4 (0.46) | SMN1; SMN2TSHRDAPK1CYP2D6HDAC4 | |
| SCHEMBL31282188 | 0.74 | CYP2D6 (0.42) | SMN1; SMN2TSHRDAPK1CYP2D6HTT | |
| SCHEMBL454643 | 0.74 | PDE4B (0.54) | HDAC4HDAC2HDAC8HDAC6HTT | |
| SCHEMBL29001722 | 0.74 | PDE4B (0.58) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL21794267 | 0.73 | TSHR (0.41) | SMN1; SMN2TSHRDAPK1CYP2D6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555402-A | Metathesis catalyst and reaction using the same | XIMO AG | 2016-05-04 | — | — | CN | disclosed |