Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370458 | 0.87 | CYP2D6 (0.41) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL28019701 | 0.87 | PGAM1 (0.49) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL2521856 | 0.85 | TSHR (0.39) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL28020176 | 0.85 | HDAC4 (0.46) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL28614880 | 0.85 | TSHR (0.41) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL3185678 | 0.81 | PTGS2 (0.39) | TSHRSMN1; SMN2BCL2L1PTPN1CHAT | |
| SCHEMBL2525532 | 0.80 | PTGS2 (0.42) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL30166504 | 0.80 | PTGS2 (0.42) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL8368643 | 0.79 | HDAC4 (0.52) | HDAC4HDAC2HDAC8HDAC6PGAM1 | |
| SCHEMBL28147663 | 0.79 | TSHR (0.40) | HDAC4HDAC2HDAC8HDAC6PGAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565546-A | Condensation product and use thereof as dispersant for pitch in water slurry | NIKKA CHEMICAL INDUSTRY CO. (JP) | 1986-01-21 | — | — | US | claimed |
| US-4565546-A | Condensation product and use thereof as dispersant for pitch in water slurry | NIKKA CHEMICAL INDUSTRY CO. (JP) | 1986-01-21 | — | — | US | disclosed |