SCHEMBL454643

SCHEMBL454643

Oc1c(-c2ccccc2)c(O)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.54
PDE4A P27815 3/20 0.54
PDE4C Q08493 3/20 0.54
PDE4D Q08499 3/20 0.54
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
MAPT P10636 2/20 0.46
BCL2L1 Q07817 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
MMP3 P08254 1/20 0.46
ALDH1A1 P00352 2/20 0.44
BACE1 P56817 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HNF4A P41235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14353864 0.97 PDE4B (0.50) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL1754108 0.94 PDE4B (0.52) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL29001722 0.94 PDE4B (0.58) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL8644874 0.91 PDE4A (0.50) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL19253312 0.88 HDAC4 (0.52) PDE4BPDE4APDE4CPDE4DHDAC4
Phosphoric Acid SCHEMBL1199529 0.88 PDE4A (0.45) PDE4BPDE4APDE4CPDE4DHDAC4
Phosphoric Acid SCHEMBL5679956 0.88 PDE4A (0.45) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL29287283 0.87 MMP3 (0.67) PDE4BPDE4APDE4CPDE4DMAPT
SCHEMBL4598394 0.85 PDE4B (0.56) PDE4BPDE4APDE4CPDE4DHDAC4
SCHEMBL29351253 0.84 PDE4B (0.47) PDE4BPDE4APDE4CPDE4DHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115466476-A Preparation method of PMI foam with wave absorbing performance and flame retardant performance 湖南兆恒材料科技有限公司 2022-12-13 CN claimed
CN-113998931-A Preparation method of kaolin polymer-based regenerated EPS (expandable polystyrene) building exterior wall thermal insulation material 惠州市广润环保科技有限公司 2022-02-01 CN claimed
CN-113831442-A High-cost-performance flame-retardant polymethacrylimide foam and preparation method thereof 湖南兆恒材料科技有限公司 2021-12-24 CN claimed
CN-109844003-B Flame retardant propylene compositions SABIC环球技术有限责任公司 2021-05-11 CN claimed
CN-112739757-A Glass fiber filled flame retardant polypropylene composition SABIC环球技术有限责任公司 2021-04-30 CN claimed
CN-109666287-B Solvent-free waterborne polyurethane/sulfonated calixarene modified hydrotalcite nanocomposite and preparation method thereof 陕西科技大学 2021-04-06 CN claimed
EP-3491056-B1 FLAME RETARDANT PROPYLENE COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-06-03 EP claimed
EP-2935430-B1 FLAME RETARDANT POLYMER COMPOSITIONS BYK USA INC (US) 2019-05-29 EP claimed
CN-109796748-A A kind of flame-retardant and anti-static thermoplastic polyurethane elastomer and its preparation method and application 美瑞新材料股份有限公司 2019-05-24 CN claimed
CN-109666287-A A kind of no-solvent type aqueous polyurethane/Sulfonated calixarenes modified hydrotalcite nanocomposite and preparation method thereof 陕西科技大学 2019-04-23 CN claimed
US-20040097620-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US claimed
US-20040097619-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US claimed
WO-2004035671-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-29 WO claimed
EP-1379584-A1 FLAME RETARDANT COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-14 EP claimed
US-20040002559-A1 Flame retardant coatings CIBA SPECIALTY CHEMICALS CORP. 2004-01-01 US claimed
US-20030207969-A1 Flame retardant compositions CAPOCCI GERALD A (US) 2003-11-06 US claimed
WO-2003087211-A2 FLAME RETARDANT POLYMER COMPOSITIONS CONTAINING HYDROXYLAMINE ESTERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-10-23 WO claimed
WO-2003085039-A1 FLAME RETARDANT COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-10-16 WO claimed
WO-2003050175-A2 FLAME RETARDANT CONPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-19 WO claimed
WO-2002074847-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 2002-09-26 WO claimed