Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21056248 | 0.94 | — | — | |
| Bicarbonate SCHEMBL14829871 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10869743 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL28168658 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL209656 | 0.94 | — | — | |
| Bicarbonate SCHEMBL4527463 | 0.94 | — | — | |
| Bicarbonate SCHEMBL4527467 | 0.94 | — | — | |
| Bicarbonate SCHEMBL21056247 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5572362 | 0.88 | — | — | |
| Bicarbonate SCHEMBL6013375 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980841-A | Rapid small volume detection of blood ammonia | 斯坦福大学托管董事会 | 2016-09-28 | — | — | CN | claimed |
| CN-107074966-A | The Fc region variants of FCRN and albumin A binding property with change | 豪夫迈·罗氏有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-105899534-A | Fc region variants with modified FCRN and maintained protein A binding properties | 豪夫迈·罗氏有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105873948-A | Fc region variants with modified FCRN binding properties | 豪夫迈·罗氏有限公司 | 2016-08-17 | — | — | CN | disclosed |