Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14829871 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4527467 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11210036 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28064756 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27737498 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10909607 | 0.94 | — | — | |
| Bicarbonate SCHEMBL4735636 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5458669 | 0.93 | — | — | |
| Bicarbonate SCHEMBL8535954 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL5458673 | 0.93 | CA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100128-B | Synthetic method of Ribocini intermediate product and intermediate compound thereof | 广安凯特制药有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-111100128-A | Synthetic method of Ribocini intermediate product and intermediate compound thereof | 广安凯特制药有限公司 | 2020-05-05 | — | — | CN | claimed |
| CN-118085643-A | Dispersion containing nano material and preparation method and application thereof | 中国科学院化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-116598146-A | Cotton straw-based porous carbon material and preparation method and application thereof | 新疆理工学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-116500174-A | Method for detecting total EPA in plasma or blood cells by utilizing HPLC-MS/MS | 无锡观合医学检验所有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-111100128-B | Synthetic method of Ribocini intermediate product and intermediate compound thereof | 广安凯特制药有限公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-2978449-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION | GLOBEIMMUNE INC (US) | 2021-09-08 | — | — | EP | disclosed |
| US-10849971-B2 | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection | GLOBEIMMUNE, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| CN-111100128-A | Synthetic method of Ribocini intermediate product and intermediate compound thereof | 广安凯特制药有限公司 | 2020-05-05 | — | — | CN | disclosed |
| US-20190240320-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION | GLOBEIMMUNE, INC. | 2019-08-08 | — | — | US | disclosed |
| US-10265393-B2 | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection | GLOBEIMMUNE, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-5772994-A | Hematopoietic facilitatory cells and their uses | THE UNIVERSITY OF PITTSBURGH (US) | 1998-06-30 | — | — | US | disclosed |
| US-5698171-A | DESULFURIZATION; USING AQUEOUS SCAVENGER MIXTURE | QUAKER CHEMICAL CORPORATION (US) | 1997-12-16 | — | — | US | disclosed |
| WO-1997025126-A2 | REGENERATIVE METHOD AND COMPOSITION FOR REMOVING SULFIDES FROM GAS STREAMS | QUAKER CHEMICAL CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |
| EP-0652943-A4 | HEMATOPOIETIC FACILITATORY CELLS AND THEIR USES. | UNIV PITTSBURGH (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0652943-A1 | HEMATOPOIETIC FACILITATORY CELLS AND THEIR USES | UNIVERSITY OF PITTSBURGH (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5376545-A | Culture product of Cellulomonas | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| CN-1091955-A | Hematopoietic facilitatory cells | UNIV PITTSBURGH (US) | 1994-09-14 | — | — | CN | disclosed |
| WO-1994001534-A1 | HEMATOPOIETIC FACILITATORY CELLS AND THEIR USES | THE UNIVERSITY OF PITTSBURGH (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5100378-A | Lymph cells, infusion and blocking agents | NEORX CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |