Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27446593 | 0.94 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL7197828 | 0.92 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27810959 | 0.88 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27631014 | 0.88 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27638228 | 0.81 | — | — | |
| SCHEMBL27619041 | 0.72 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27619048 | 0.71 | — | — | |
| SCHEMBL27638245 | 0.67 | NPC1 (0.32) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27729830 | 0.66 | — | — | |
| SCHEMBL27476175 | 0.64 | ACHE (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566519-A | Supported metallocene catalyst and preparation method and application thereof | CHINA PETROLEUM & CHEM CORP | 2016-05-11 | — | — | CN | disclosed |