Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27446593 | 0.98 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27631014 | 0.92 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28064767 | 0.92 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27810959 | 0.92 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27638228 | 0.83 | — | — | |
| SCHEMBL27619041 | 0.74 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27619048 | 0.72 | — | — | |
| SCHEMBL27890297 | 0.70 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27476175 | 0.70 | ACHE (0.38) | ACHEBACE1 | |
| SCHEMBL1027608 | 0.67 | ACHE (0.39) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100358923-C | Polymerization Process Using Metallocene Catalyst System | UNIVATION TECH LLC (US) | 2008-01-02 | — | — | CN | claimed |
| CN-1805977-A | Polymerization Process Using Metallocene Catalyst System | UNIVATION TECH LLC (US) | 2006-07-19 | — | — | CN | claimed |
| US-20230242683-A1 | PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2023-08-03 | — | — | US | disclosed |
| CN-115023446-A | Process for preparing catalyst and catalyst composition | 台塑工业美国公司 | 2022-09-06 | — | — | CN | disclosed |
| US-11001657-B2 | Unbridged indacenyl metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20190119418-A1 | Unbridged Indacenyl Metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-04-25 | — | — | US | disclosed |
| CN-103788235-B | A kind of carried metallocene catalyst carrier and metallocene catalyst | 中国石油化工股份有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-103788275-B | A kind of method of preparing low density polyethylene (LDPE) | SINOPEC CORP. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-105273115-A | Low-temperature-suitable polyethylene and injection moulding composition | CHINA PETROLEUM & CHEMICAL | 2016-01-27 | — | — | CN | disclosed |
| CN-105102489-A | Metallocene catalyst system comprising antistatic agent and method for preparing polyolefin using the same | HANWHA CHEMICAL CORP | 2015-11-25 | — | — | CN | disclosed |
| CN-103087240-B | Method for preparing ethylene polymer | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |
| CN-1400227-A | Polythene catalyst loaded by semi-metallocene | CHINA PETROCHEMICAL CORP (CN) | 2003-03-05 | — | — | CN | disclosed |
| EP-1066296-B1 | NOVEL DENDRIMER COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS CATALYSTS | BAYER AG (DE) | 2002-09-04 | — | — | EP | disclosed |
| CN-1367800-A | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2002-09-04 | — | — | CN | disclosed |
| CN-1364817-A | Magnesium halide/silicon dioxide loaded semi-metallocene catalyst and its preparation and use | CHINA PETROCHEMICAL CORP (CN) | 2002-08-21 | — | — | CN | disclosed |
| US-6403735-B1 | REACTING TRANSITION METAL COMPOUND WITH FULVENE COMPOUND IN PRESENCE OF REDUCING AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| CN-1345887-A | Semi-metallocene supported polyvinyl catalyst and preparation method thereof | CHINA PETROCHEMICAL CORP (CN) | 2002-04-24 | — | — | CN | disclosed |
| US-20020010084-A1 | Method for producting fulvene metal complexes | BECKE SIGURD (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6258744-B1 | OLEFIN POLYMERIZATION CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-1063243-A2 | Olefin polymerization process and catalyst system therefor | BAYER AG (DE) | 2000-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001657-B2 | Unbridged indacenyl metallocenes | MT-ND4L, MT-ND4, ACSL4 | NPC1 2701/4885HPGD 2194/4885MAPK1 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.