Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18633267 | 0.90 | TSHR (0.47) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11857468 | 0.90 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL20924844 | 0.88 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL5322687 | 0.88 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL28101040 | 0.83 | TSHR (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6418608 | 0.82 | TSHR (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10720114 | 0.80 | TSHR (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL468460 | 0.80 | TSHR (0.44) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL177943 | 0.80 | CYP3A4 (0.48) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL27898356 | 0.78 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555402-B | Metathesis catalyst and reaction using the same | 西莫有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-105555402-A | Metathesis catalyst and reaction using the same | XIMO AG | 2016-05-04 | — | — | CN | disclosed |