SCHEMBL468460

SCHEMBL468460

C=CCOC(=O)C(=C)CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 3/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.32
KDM4E B2RXH2 1/20 0.32
THRB P10828 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28306229 0.96 TSHR (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL350218 0.84 TSHR (0.36) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL4698282 0.83 TSHR (0.50) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL3797444 0.83 CYP3A4 (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL11805885 0.81 THRB (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9640142 0.81 ALDH1A1 (0.31) TSHRALDH1A1THRBSOAT1
SCHEMBL3834150 0.80 TSHR (0.56) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL175301 0.80 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2549360 0.80 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL6418608 0.80 TSHR (0.46) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801341-B Graphene heat-conducting insulating silicon wafer and preparation method thereof 江苏诺德新材料股份有限公司 2024-07-09 CN claimed
CN-118063672-A Composition and preparation method thereof, composite electrode and preparation method thereof, and battery 浙江正泰电器股份有限公司 2024-05-24 CN claimed
CN-117801341-A Graphene heat-conducting insulating silicon wafer and preparation method thereof 江苏诺德新材料股份有限公司 2024-04-02 CN claimed
CN-114478937-B Water-retaining polycarboxylate water reducer for machine-made sand concrete and preparation method thereof 厦门市建筑科学研究院有限公司 2024-03-01 CN claimed
CN-114605885-B Double-component back coating material for rock plate and preparation method thereof 河北匠工新型建筑材料有限公司 2023-04-25 CN claimed
CN-115787350-A Paper fluorine-containing deacidification liquid 国家图书馆 2023-03-14 CN claimed
CN-218047807-U Be applied to rabbling mechanism of perfluoroalkyl ethyl acrylate preparation 四川上氟科技有限公司 2022-12-16 CN claimed
CN-114478937-A Water-retaining polycarboxylate superplasticizer for machine-made sand concrete and preparation method thereof 厦门市建筑科学研究院有限公司 2022-05-13 CN claimed
CN-113169335-A Electrode composition for cathode of battery cell of lithium ion battery, cathode slurry composition comprising same, cathode and battery 阿朗新科德国有限责任公司 2021-07-23 CN claimed
CN-111411515-A Fluorine-free water repellent agent, preparation method thereof and water repellent fabric 远东新世纪股份有限公司 2020-07-14 CN claimed
CN-102250279-B Self-crosslinked fluorosilicate acrylic resin and preparation method thereof JINZHOU HUIFA TIANHE CHEMICALS CO LTD 2013-05-08 CN claimed
CN-102229777-B Hydrophobic olephobic epoxy paint and its preparation and application method UNIV HEBEI TECHNOLOGY 2013-04-17 CN claimed
CN-102250280-B Perfluoro alkyl ethyl acrylic ester-modified single-component acrylic resin and preparation method as well as application thereof JINZHOU HUIFATIANHE CHEMICAL CO LTD 2013-04-17 CN claimed
CN-102219878-B Hydroxylated acrylic resin as well as preparation method and application thereof JINZHOU HUIFATIANHE CHEMICAL CO LTD 2013-04-17 CN claimed
CN-102174143-B Method for preparing fluorine-containing acrylate emulsion JINZHOU HUIFA TIANHE CHEMICAL CO LTD 2013-01-09 CN claimed
CN-102421809-A Cationic comb copolymers, preparation thereof and use thereof in cosmetic, pharmaceutical and dermatological formulations CLARIANT INT LTD 2012-04-18 CN claimed
US-20100159234-A1 Adhesive film composition for electric and electronic devices and adhesive film using the same CHEIL INDUSTRIES, INC. (KR) 2010-06-24 US claimed
US-20070270542-A1 Crosslinkable Polymer Systems REICHHOLD, INC. 2007-11-22 US claimed
WO-2006041553-A1 CROSSLINKABLE POLYMER SYSTEMS REICHHOLD, INC. (US) 2006-04-20 WO claimed
US-20060079624-A1 Crosslinkable polymer systems REICHHOLD, INC. 2006-04-13 US claimed