SCHEMBL28064781

SCHEMBL28064781

CCCCCCCCCCCCCCCCCCCCCCCCCCCCOCC(O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 7/20 1.00
LPAR1 Q92633 14/20 0.69
LPAR3 Q9UBY5 11/20 0.69
LPAR2 Q9HBW0 8/20 0.61
LPAR4 Q99677 6/20 0.61
LPAR6 P43657 5/20 0.61
ENPP2 Q13822 3/20 0.61
USP2 O75604 1/20 0.59
HTT P42858 1/20 0.57
P2RY10 O00398 1/20 0.56
CES2 O00748 1/20 0.53
TRPV1 Q8NER1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258136 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7820593 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL26603866 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258118 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL12621099 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7829804 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258161 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258032 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258094 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL250888 0.98 LPAR5 (0.97) LPAR5LPAR1LPAR3LPAR2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105641714-A Folic acid modified VEGFR2/Tie2 double gene composition 四川大学 2016-06-08 CN disclosed