SCHEMBL258032

SCHEMBL258032

CCCCCCCCCCCCCCCCOCC(O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 7/20 1.00
LPAR1 Q92633 14/20 0.69
LPAR3 Q9UBY5 11/20 0.69
LPAR2 Q9HBW0 8/20 0.61
LPAR4 Q99677 6/20 0.61
LPAR6 P43657 5/20 0.61
ENPP2 Q13822 3/20 0.61
USP2 O75604 1/20 0.59
HTT P42858 1/20 0.57
P2RY10 O00398 1/20 0.56
CES2 O00748 1/20 0.53
TRPV1 Q8NER1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258136 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7820593 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL28064781 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL26603866 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258118 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL12621099 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7829804 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258161 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258094 1.00 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL250888 0.98 LPAR5 (0.97) LPAR5LPAR1LPAR3LPAR2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110464709-A For treating the neuroprotective liposome composition and method of apoplexy UNIV TEXAS 2019-11-19 CN claimed
CN-105637081-B Method for forming lipid bilayer on biochip 吉尼亚科技公司 2018-06-01 CN claimed
CN-107106708-A MRI Imaging of Amyloid Plaques Using Liposomes 德克萨斯州儿童医院 2017-08-29 CN claimed
CN-117615752-A RNA compositions comprising buffer substances and methods of making, storing, and using the same 生物技术欧洲股份公司 2024-02-27 CN disclosed
CN-110464709-A For treating the neuroprotective liposome composition and method of apoplexy UNIV TEXAS 2019-11-19 CN disclosed
CN-110114068-A Lipid particle composition and medical composition 富士胶片株式会社 2019-08-09 CN disclosed
CN-109999013-A Inhalable dry powder doses 普马特里克斯营业公司 2019-07-12 CN disclosed
CN-109937046-A Liposome anticancer composition 艾利西斯股份有限公司 2019-06-25 CN disclosed
CN-109477071-A The 3D printing of cellularised bracket 牛津大学创新有限公司 2019-03-15 CN disclosed
CN-105142681-B Semi-fluorocarbon containing contrast agents 贝朗医疗有限公司 2019-03-12 CN disclosed
CN-109415723-A IMPROVED PROMOTERS AND COMPOSITIONS 牛津大学创新有限公司 2019-03-01 CN disclosed
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORPORATION (JP) 2008-09-25 US disclosed
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers KAO CORPORATION (JP) 2004-01-15 US disclosed
EP-1325737-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS Kao Corporation (JP) 2003-07-09 EP disclosed
EP-1133287-A2 USE OF 17-KETOSTEROIDS FOR THE TREATMENT OF HEPATITIS C VIRUS AND OTHER TOGAVIRUSES Hollis-Eden Pharmaceuticals Inc. (US) 2001-09-19 EP disclosed
WO-2000035472-A2 CYTOKINE COMBINATION THERAPY HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-06-22 WO disclosed
WO-2000032177-A2 USE OF 17-KETOSTEROIDS IN THE TREATMENT OF HEPATITIS C VIRUS AND OTHER TOGAVIRUS INFECTIONS HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-06-08 WO disclosed
WO-1998047516-A1 COMBINATION THERAPY UTILISING 17-KETOSTEROIDS AND INTERLEUKIN INHIBITORS, OR INTERLEUKIN-10 POTIONALLY WITH INTERLEUKIN INHIBITORS PRENDERGAST PATRICK T (IE) 1998-10-29 WO disclosed
US-5804552-A COMPOUND CONSISTING OF TYROSINE OR HYDROXYPROLINE LINKED TO PHOSPHOLIPID BY PHOSPHOESTER BOND THROUGH HYDROXYL GROUP; CAPABLE OF CONJUGATION WITH THERAPEUTIC PEPTIDE NEXSTAR PHARMACEUTICALS, INC. (US) 1998-09-08 US disclosed
US-5554728-A Lipid conjugates of therapeutic peptides and protease inhibitors NEXSTAR PHARMACEUTICALS, INC. (US) 1996-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers CUTA, DSG1, OGA LPAR5 115/4885LPAR1 26/4885LPAR3 77/4885
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS DSG1, CUTA, OGA LPAR5 265/4885LPAR1 43/4885LPAR3 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.