Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505612 | 0.87 | MAPT (0.51) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL27183715 | 0.85 | MAPT (0.51) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL20140111 | 0.83 | MAPT (0.54) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL20076106 | 0.82 | MAPT (0.49) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL30033027 | 0.81 | MAPT (0.48) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL31623073 | 0.81 | MAPT (0.52) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL15754287 | 0.81 | ALDH1A1 (0.52) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL20046277 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL30432629 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL4941010 | 0.80 | LMNA (0.51) | MAPTALDH1A1LMNAPDK2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105712945-B | 2-substituted oxy-5-methylsulfonyl aryl piperazine amide analogue and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-105712945-A | 2-Substituted-oxy-5-methylsulfonyl aryl piperazine acidamide analogue and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2016-06-29 | — | — | CN | disclosed |