Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114461 | 0.77 | ALDH1A1 (0.89) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| SCHEMBL14543272 | 0.76 | ALDH1A1 (0.73) | ALDH1A1CYP3A4MAPK1FAAHLMNA | |
| SCHEMBL2814224 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HSD17B10LMNAKDM4EGAA | |
| Metolcarb SCHEMBL118244 | 0.75 | LMNA (0.65) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| Metolcarb SCHEMBL29413999 | 0.75 | LMNA (0.65) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| Phenmedipham SCHEMBL8489570 | 0.74 | CYP3A4 (1.00) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| Phenmedipham SCHEMBL29516822 | 0.74 | CYP3A4 (1.00) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| SCHEMBL29250428 | 0.74 | GAA (0.58) | ALDH1A1CYP3A4MAPK1LMNAKDM4E | |
| Phenmedipham SCHEMBL54580 | 0.74 | CYP3A4 (1.00) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 | |
| Metolcarb SCHEMBL7079404 | 0.73 | LMNA (0.62) | ALDH1A1CYP3A4MAPK1FAAHHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ALDH1A1 401/4885CYP3A4 1909/4885MAPK1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.