Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401010 | 0.85 | CFB (0.38) | CFBCHRNA7KDM1AMAOAMAOB | |
| Tert-Butyl Formate SCHEMBL28065009 | 0.85 | KDM1A (0.34) | CHRNA7KDM1AMAOAMAOB | |
| Tert-Butyl Formate SCHEMBL28065029 | 0.78 | TDP1 (0.34) | KDM1AMAOAMAOB | |
| Tert-Butyl Formate SCHEMBL27807762 | 0.75 | TDP1 (0.41) | KDM1A | |
| Tert-Butyl Formate SCHEMBL27790496 | 0.71 | TDP1 (0.37) | — | |
| Tert-Butyl Formate SCHEMBL28065019 | 0.71 | PRCP (0.31) | — | |
| Tert-Butyl Formate SCHEMBL27807751 | 0.70 | TDP1 (0.36) | KDM1A | |
| SCHEMBL24363923 | 0.70 | CHRNA7 (0.46) | CHRNA7KDM1AMAOAMAOB | |
| SCHEMBL29477503 | 0.70 | CHRNA7 (0.46) | CHRNA7KDM1AMAOAMAOB | |
| SCHEMBL3438950 | 0.70 | CHRNA7 (0.46) | CHRNA7KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |