Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28065028 | 0.85 | CFB (0.33) | KDM1AMAOBMAOACHRNA7 | |
| SCHEMBL16400486 | 0.84 | KDM1A (0.42) | KDM1AMAOBMAOACHRNA7SLC18A3 | |
| SCHEMBL2707339 | 0.84 | KDM1A (0.42) | KDM1AMAOBMAOACHRNA7SLC18A3 | |
| Tert-Butyl Formate SCHEMBL28065029 | 0.81 | TDP1 (0.34) | KDM1AMAOBMAOASLC6A2TDP1 | |
| SCHEMBL30661773 | 0.75 | KDM1A (0.39) | KDM1AMAOBMAOACHRNA7SLC6A2 | |
| SCHEMBL27869789 | 0.74 | SLC6A1 (0.42) | KDM1AMAOBMAOACHRNA7S1PR4 | |
| SCHEMBL28065007 | 0.74 | CHRM3 (0.38) | KDM1AMAOACHRNA7CHRM2CHRM1 | |
| Tert-Butyl Formate SCHEMBL27790496 | 0.74 | TDP1 (0.37) | SLC18A3TDP1 | |
| Tert-Butyl Formate SCHEMBL27591602 | 0.74 | TDP1 (0.46) | KDM1AMAOATDP1GBA1 | |
| SCHEMBL27915958 | 0.73 | CHRNA7 (0.44) | KDM1AMAOBMAOACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |