Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712598 | 1.00 | TSHR (0.47) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL28138992 | 1.00 | TSHR (0.47) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL27924265 | 0.96 | TSHR (0.44) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL11348207 | 0.96 | LMNA (0.44) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL27924266 | 0.92 | LMNA (0.41) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL8050134 | 0.88 | — | — | |
| SCHEMBL10714917 | 0.87 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL18869613 | 0.87 | TSHR (0.71) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2634003 | 0.87 | FOLH1 (0.57) | TSHRLMNANFKB1PMP22HDAC3 | |
| SCHEMBL19741462 | 0.87 | FOLH1 (0.57) | TSHRLMNANFKB1PMP22HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452261-A | Continuous process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MAT INC | 2016-03-30 | — | — | CN | disclosed |