Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050134 | 0.92 | — | — | |
| SCHEMBL15345209 | 0.87 | LMNA (0.69) | LMNANFKB1TSHRPMP22FOLH1 | |
| SCHEMBL2634003 | 0.84 | FOLH1 (0.57) | LMNANFKB1TSHRPMP22FOLH1 | |
| SCHEMBL169155 | 0.84 | — | — | |
| SCHEMBL10714917 | 0.84 | TSHR (0.71) | LMNANFKB1TSHRPMP22FOLH1 | |
| SCHEMBL9169879 | 0.84 | PAOX (0.52) | LMNACES2CES1AKR1B1MAPT | |
| SCHEMBL14507056 | 0.84 | — | — | |
| SCHEMBL18869613 | 0.84 | TSHR (0.71) | LMNANFKB1TSHRPMP22FOLH1 | |
| SCHEMBL6717827 | 0.84 | — | — | |
| SCHEMBL19741462 | 0.84 | FOLH1 (0.57) | LMNANFKB1TSHRPMP22FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107427612-A | Medical devices degradable on demand | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-105102465-A | Catalytic process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MAT INC | 2015-11-25 | — | — | CN | claimed |
| CN-101258183-B | Polymers comprising thioester bonds | DSM IP ASSETS BV | 2011-01-26 | — | — | CN | claimed |
| CN-101258183-A | Polymers comprising thioester bonds | DSM IP ASSETS BV (NL) | 2008-09-03 | — | — | CN | claimed |
| CN-101184767-A | Aqueous catalytic process for the preparation of thiocarboxylate silane | GEN ELECTRIC (US) | 2008-05-21 | — | — | CN | claimed |
| CN-104342049-B | Bonding sheet and optical component | 日东电工株式会社 | 2019-07-23 | — | — | CN | disclosed |
| CN-104342053-B | Surface protective film and optical component | 日东电工株式会社 | 2019-06-11 | — | — | CN | disclosed |
| CN-104342050-B | Bonding sheet and optical component | 日东电工株式会社 | 2019-06-07 | — | — | CN | disclosed |
| CN-104342052-B | Surface protective film and optical component | 日东电工株式会社 | 2019-05-14 | — | — | CN | disclosed |
| CN-109628004-A | Film, surface protective film and optical component with finishing coat | 日东电工株式会社 | 2019-04-16 | — | — | CN | disclosed |
| US-20180360830-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF AGELASTATIN ALKALOIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-12-20 | — | — | US | disclosed |
| CN-108977131-A | Adhesive composition, surface protective plate and optical component | 日东电工株式会社 | 2018-12-11 | — | — | CN | disclosed |
| US-20090156707-A1 | Polymers comprising thioester bonds | DSM IP ASSETS B.V. (NL) | 2009-06-18 | — | — | US | disclosed |
| CN-100422193-C | Method for producing thiocarboxylate silane | GEN ELECTRIC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-101258183-A | Polymers comprising thioester bonds | DSM IP ASSETS BV (NL) | 2008-09-03 | — | — | CN | disclosed |
| CN-101184767-A | Aqueous catalytic process for the preparation of thiocarboxylate silane | GEN ELECTRIC (US) | 2008-05-21 | — | — | CN | disclosed |
| CN-1946831-A | Hydrotreating catalyst containing a group V metal | ALBEMARLE NETHERLANDS BV (NL) | 2007-04-11 | — | — | CN | disclosed |
| EP-0000283-B1 | SUBSTITUTED CARBAMATES, PREPARATION AND COMPOSITIONS THEREOF AND USE THEREOF AS INSECTICIDES. | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-10-14 | — | — | EP | disclosed |
| US-4160034-A | INSECTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| EP-0000283-A1 | Substituted carbamates, preparation and compositions thereof and use thereof as insecticides. | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180360830-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF AGELASTATIN ALKALOIDS | DIMT1, CIAPIN1, INMT | LMNA 862/4885NFKB1 4007/4885TSHR 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.