2-Picolinic Acid

2-Picolinic Acid

SCHEMBL28065051

C=C(C)C(=O)O.O=C(O)c1ccccn1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.74
L3MBTL1 Q9Y468 2/20 0.74
NAPRT Q6XQN6 1/20 0.74
P4HTM Q9NXG6 1/20 0.74
ALDH1A1 P00352 3/20 0.60
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
KMT2A Q03164 3/20 0.52
KDM4E B2RXH2 4/20 0.47
GSK3B P49841 1/20 0.46
CTNNB1 P35222 1/20 0.45
WNT3A P56704 1/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
PKM P14618 2/20 0.45
MAPT P10636 1/20 0.45
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MITF O75030 1/20 0.43
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL1831091 0.89 LMNA (0.80) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL27945864 0.88 LMNA (0.87) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL27658889 0.88 LMNA (0.87) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL5694340 0.88 LMNA (0.87) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL27417660 0.86 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL28175513 0.86 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL28737810 0.86 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL29368665 0.86
2-Picolinic Acid SCHEMBL674837 0.86 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMALDH1A1
2-Picolinic Acid SCHEMBL7457912 0.86 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105582901-A Preparation of adsorbent of long carbon chain biatomic acid fermentation solution WANG JINMING 2016-05-18 CN disclosed