Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12129521 | 1.00 | PTGS2 (0.49) | PTGS2NR1H4LMNAPTGS1AKR1C3 | |
| SCHEMBL966466 | 0.85 | LMNA (0.41) | LMNAADRB3CXCR1CXCR2BLM | |
| SCHEMBL966639 | 0.85 | EPHX1 (0.47) | LMNAADRB3BLMADRB2ADRB1 | |
| SCHEMBL25167208 | 0.85 | EPHX1 (0.47) | LMNAADRB3BLMADRB2ADRB1 | |
| SCHEMBL16322044 | 0.85 | LMNA (0.41) | LMNAADRB3CXCR1CXCR2BLM | |
| SCHEMBL15456905 | 0.84 | LMNA (0.56) | PTGS2NR1H4LMNAPTGS1AKR1C3 | |
| SCHEMBL27602626 | 0.84 | PTGS2 (0.50) | PTGS2NR1H4LMNAPTGS1AKR1C3 | |
| SCHEMBL1345262 | 0.84 | LMNA (0.56) | PTGS2NR1H4LMNAPTGS1AKR1C3 | |
| SCHEMBL1345370 | 0.84 | LMNA (0.56) | PTGS2NR1H4LMNAPTGS1AKR1C3 | |
| SCHEMBL27602625 | 0.84 | PTGS2 (0.50) | PTGS2NR1H4LMNAPTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722972-A | Cellular factors involved in the cytotoxicity of leukocidins of staphylococcus aureus: novel therapeutic target | 纽约大学 | 2016-06-29 | — | — | CN | disclosed |