SCHEMBL2806516

SCHEMBL2806516

CC(N)C(O)CC(N)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.44
TRPA1 O75762 1/20 0.44
TDP1 Q9NUW8 1/20 0.38
SPHK1 Q9NYA1 2/20 0.38
TSHR P16473 1/20 0.33
CYP2D6 P10635 2/20 0.31
LMNA P02545 2/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CETP P11597 1/20 0.31
HTT P42858 1/20 0.31
UBE2N P61088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131967 0.78
SCHEMBL5517670 0.77
SCHEMBL1132477 0.77
SCHEMBL5234419 0.77
SCHEMBL15209529 0.77
SCHEMBL15209859 0.77
SCHEMBL143927 0.75
SCHEMBL10889704 0.75
SCHEMBL143928 0.75
SCHEMBL607966 0.75 ANPEP (0.52) TDP1TSHRCYP2D6LMNAGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100240894-A1 METHOD FOR PRODUCING AMINES FROM GLYCERIN BASF SE (DE) 2010-09-23 US disclosed
EP-2185499-A1 METHOD FOR PRODUCING AMINES FROM GLYCERIN BASF SE (DE) 2010-05-19 EP disclosed
WO-2009027248-A1 METHOD FOR PRODUCING AMINES FROM GLYCERIN BASF SE (DE) 2009-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240894-A1 METHOD FOR PRODUCING AMINES FROM GLYCERIN GNMT, GK, GMPS TRPV1 1268/4885TRPA1 847/4885TDP1 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.