Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302078 | 0.85 | MAPT (0.55) | MAPTMEN1KMT2AKDM4EPOLQ | |
| SCHEMBL16454401 | 0.83 | JUN (0.43) | MAPTMEN1KMT2AASPHKDM4E | |
| SCHEMBL13468557 | 0.83 | KDM4E (0.56) | MAPTGAAKDM4EGLA | |
| SCHEMBL26333848 | 0.81 | ASPH (0.41) | MAPTMEN1KMT2AASPHGAA | |
| SCHEMBL17816469 | 0.81 | MAPT (0.41) | MAPTMEN1KMT2AASPHKDM4E | |
| SCHEMBL27743600 | 0.81 | ASPH (0.43) | MAPTMEN1KMT2AASPHGAA | |
| SCHEMBL1105997 | 0.80 | ASPH (0.54) | KMT2AASPHKDM4ECES2GABRA5 | |
| SCHEMBL28183587 | 0.77 | MAPT (0.44) | MAPTMEN1KMT2AASPHNPSR1 | |
| SCHEMBL16454312 | 0.75 | KMT2A (0.46) | MEN1KMT2AASPHGAAKDM4E | |
| SCHEMBL20320529 | 0.75 | MAPT (0.45) | MAPTASPHNPSR1CES2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103269592-B | Cyclic amine substituted oxazolidinone CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-05-11 | — | — | CN | disclosed |