Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA3 | P07451 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL28065272 | 0.85 | LMNA (0.47) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL314829 | 0.83 | CA9 (0.77) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL27598031 | 0.81 | CA9 (0.80) | ALDH1A1CA9CA12CA1CA2 | |
| 3-Hydroxycoumarin SCHEMBL27550346 | 0.80 | HPGD (0.63) | ALDH1A1CA9CA12CA1CA3 | |
| SCHEMBL1491019 | 0.79 | CA9 (0.62) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL1090505 | 0.79 | CA12 (0.83) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL25431834 | 0.79 | CA12 (0.91) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL9456088 | 0.79 | CA9 (0.69) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL28497123 | 0.79 | CA12 (0.69) | ALDH1A1CA9CA12CA1CA2 | |
| Coumarin SCHEMBL28058644 | 0.79 | CA9 (0.69) | ALDH1A1CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965150-B | Scopoletin derivant and its preparation method and application | 广州康臣药物研究有限公司 | 2016-06-15 | — | — | CN | disclosed |