Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447254 | 0.84 | KDM1A (0.53) | KDM1APIN1 | |
| SCHEMBL16447253 | 0.84 | KDM1A (0.53) | KDM1APIN1 | |
| SCHEMBL18043479 | 0.83 | PHGDH (0.50) | KDM1APIN1PHGDHCD274 | |
| SCHEMBL16447454 | 0.83 | PHGDH (0.50) | KDM1APIN1PHGDHCD274 | |
| SCHEMBL16455182 | 0.82 | KDM1A (0.53) | KDM1AALDH1A1PHGDH | |
| SCHEMBL16455163 | 0.82 | KDM1A (0.53) | KDM1APIN1PHGDHCD274 | |
| SCHEMBL16447279 | 0.81 | KDM1A (0.51) | KDM1A | |
| SCHEMBL20924673 | 0.81 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16447281 | 0.81 | KDM1A (0.51) | KDM1A | |
| SCHEMBL19466143 | 0.80 | PHGDH (0.52) | ALDH1A1HPGDPHGDHCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105592888-A | Kdm1a inhibitors for the treatment of disease | IMAGO BIOSCIENCES INC | 2016-05-18 | — | — | CN | disclosed |