Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003233 | 0.98 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL28800940 | 0.95 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL27597544 | 0.95 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL10794983 | 0.85 | MAPT (0.33) | TSHRSMN1; SMN2MAPTLMNACYP2C19 | |
| SCHEMBL587894 | 0.80 | ALDH1A1 (0.43) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL28910405 | 0.79 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL4774786 | 0.76 | NPSR1 (0.42) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL28163178 | 0.76 | CES1 (0.40) | TSHRSMN1; SMN2ALDH1A1CES1CES2 | |
| SCHEMBL1653521 | 0.76 | CA2 (0.42) | TSHRALDH1A1CES1CES2DAO | |
| SCHEMBL1500738 | 0.76 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALDH1A1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106939813-A | Equipment for after-treatment for the gas extraction system of vehicle | 现代自动车株式会社 | 2017-07-11 | — | — | CN | disclosed |
| CN-104371708-B | A kind of surperficial carboxylic fluorescent microballoon with crosslinked shell structure and preparation method thereof | SOOCHOW UNIVERSITY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-103154338-B | The nanofiber of biological degradability and bioaffinity excellence and manufacture method thereof | TMT MACHINERY, INC. (JP) | 2016-05-11 | — | — | CN | disclosed |