Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065646 | 0.72 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL28007548 | 0.71 | MEN1 (0.42) | MEN1KMT2AKIF11 | |
| SCHEMBL30063441 | 0.71 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL5265818 | 0.71 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL28419275 | 0.69 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL27602806 | 0.69 | KMT2A (0.53) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL29250971 | 0.69 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9AKIF11 | |
| SCHEMBL4311410 | 0.69 | MEN1 (0.53) | MEN1KMT2AKIF11MAPT | |
| SCHEMBL27700665 | 0.68 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL19810305 | 0.67 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682656-B | Compositions and methods for modulating farnesoid X receptors | 诺华股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-105682656-A | Compositions and methods for modulating farnesoid x receptors | 诺华股份有限公司 | 2016-06-15 | — | — | CN | disclosed |