Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265818 | 1.00 | MEN1 (0.57) | MEN1KMT2AKIF11SOS1CES2 | |
| SCHEMBL27511537 | 0.84 | MEN1 (0.53) | MEN1KMT2AKIF11PARP10PARP15 | |
| SCHEMBL4311410 | 0.84 | MEN1 (0.53) | MEN1KMT2AKIF11SOS1PARP10 | |
| SCHEMBL29250971 | 0.84 | MEN1 (0.53) | MEN1KMT2AKIF11PARP10RAB9A | |
| SCHEMBL27602806 | 0.84 | KMT2A (0.53) | MEN1KMT2AKIF11CES2CES1 | |
| SCHEMBL18697358 | 0.83 | CES2 (0.46) | MEN1KMT2ASOS1CES2CES1 | |
| SCHEMBL5260935 | 0.82 | MEN1 (0.52) | MEN1KMT2AKIF11 | |
| SCHEMBL17801666 | 0.82 | KMT2A (0.52) | MEN1KMT2AKIF11SOS1MAOB | |
| Hydrochloric Acid SCHEMBL28748216 | 0.82 | KMT2A (0.52) | MEN1KMT2AKIF11PARP10PARP15 | |
| SCHEMBL440172 | 0.82 | MEN1 (0.52) | MEN1KMT2AKIF11SOS1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759545-B | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2022-12-13 | — | — | CN | disclosed |