Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640337 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL3L3MBTL1LMNA | |
| SCHEMBL28865573 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL5969639 | 0.80 | HSD17B10 (0.63) | KDM4EALDH1A1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL70060 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1371748 | 0.79 | HSD17B10 (0.61) | KDM4EALDH1A1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL30775341 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL7905712 | 0.79 | KMT2A (0.50) | KDM4EALDH1A1L3MBTL3L3MBTL1LMNA | |
| SCHEMBL27787989 | 0.78 | SIGMAR1 (0.43) | KDM4EALDH1A1ALOX15 | |
| SCHEMBL12842050 | 0.76 | SMN1; SMN2 (0.46) | KDM4EALDH1A1L3MBTL3HRH3HTR7 | |
| SCHEMBL13197689 | 0.75 | TDP1 (0.42) | KDM4EALDH1A1L3MBTL3HRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683168-B | Fragrant amino pyrimidines and its application and pharmaceutical composition prepared therefrom and Pharmaceutical composition | 上海海雁医药科技有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-105683168-A | Arylamino pyramidine compound and application thereof, and pharmaceutical compositions and pharmaceutically acceptable compositions prepared therefrom | 上海海雁医药科技有限公司 | 2016-06-15 | — | — | CN | disclosed |