Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145634 | 0.82 | KDM4E (0.57) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL22835349 | 0.77 | KDM4E (0.50) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL14529544 | 0.77 | KDM4E (0.50) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL413572 | 0.75 | NAPRT (0.58) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL29488337 | 0.75 | NAPRT (0.58) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL3903137 | 0.73 | CYP1A2 (0.32) | CYP3A4TSHR | |
| SCHEMBL2627821 | 0.73 | KDM4E (0.59) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL3934370 | 0.72 | NAPRT (0.55) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL24370714 | 0.72 | KDM4E (0.45) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL29487780 | 0.72 | KDM4E (0.45) | KDM4ETDP1ALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682686-A | Vehicle and topical composition for administration | 立普妥公司 | 2016-06-15 | — | — | CN | disclosed |