(2-Nitrovinyl)Benzene

(2-Nitrovinyl)Benzene

SCHEMBL28065845

O=[N+]([O-])C=Cc1ccccc1.O=[N+]([O-])C=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 16/20 1.00
TLR4 O00206 2/20 0.69
TLR2 O60603 2/20 0.69
MEN1 O00255 1/20 0.65
S1PR4 O95977 1/20 0.65
ALDH1A1 P00352 1/20 0.65
LMNA P02545 1/20 0.65
HSP90AA1 P07900 1/20 0.65
HPGD P15428 1/20 0.65
S1PR1 P21453 1/20 0.65
MAPK1 P28482 1/20 0.65
CCR6 P51684 1/20 0.65
KMT2A Q03164 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
TLR9 Q9NR96 1/20 0.65
EGFR P00533 1/20 0.63
VCP P55072 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19088017 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL18132133 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL30590 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL1226357 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL30591 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL1226359 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
SCHEMBL7829071 0.96 FBP1 (0.91) FBP1TLR4TLR2MEN1S1PR4
SCHEMBL7829067 0.96 FBP1 (0.91) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL28758634 0.94 FBP1 (0.88) FBP1TLR4TLR2MEN1S1PR4
Hexamethylbenzene SCHEMBL29275075 0.92 FBP1 (0.84) FBP1TLR4TLR2MEN1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105682461-A Pesticidal compositions and related methods 美国陶氏益农公司 2016-06-15 CN disclosed
CN-105658059-A Pesticidal compositions and related methods 美国陶氏益农公司 2016-06-08 CN disclosed