(2-Nitrovinyl)Benzene

(2-Nitrovinyl)Benzene

SCHEMBL30591

O=[N+]([O-])C=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 16/20 1.00
TLR4 O00206 2/20 0.69
TLR2 O60603 2/20 0.69
MEN1 O00255 1/20 0.65
S1PR4 O95977 1/20 0.65
ALDH1A1 P00352 1/20 0.65
LMNA P02545 1/20 0.65
HSP90AA1 P07900 1/20 0.65
HPGD P15428 1/20 0.65
S1PR1 P21453 1/20 0.65
MAPK1 P28482 1/20 0.65
CCR6 P51684 1/20 0.65
KMT2A Q03164 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
TLR9 Q9NR96 1/20 0.65
EGFR P00533 1/20 0.63
VCP P55072 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19088017 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL18132133 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL30590 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL28065845 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL1226357 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL1226359 1.00 FBP1 (1.00) FBP1TLR4TLR2MEN1S1PR4
SCHEMBL7829071 0.96 FBP1 (0.91) FBP1TLR4TLR2MEN1S1PR4
SCHEMBL7829067 0.96 FBP1 (0.91) FBP1TLR4TLR2MEN1S1PR4
(2-Nitrovinyl)Benzene SCHEMBL28758634 0.94 FBP1 (0.88) FBP1TLR4TLR2MEN1S1PR4
Hexamethylbenzene SCHEMBL29275075 0.92 FBP1 (0.84) FBP1TLR4TLR2MEN1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2366 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136761-A Method for synthesizing pyrrole compound 南京理工大学 2025-06-13 CN claimed
CN-119798085-A Preparation method of beta-nitrostyrene 安徽泰格生物科技有限公司 2025-04-11 CN claimed
CN-119684502-A Multifunctional adhesive, preparation method and application thereof 华中科技大学 2025-03-25 CN claimed
CN-119678922-A Application of nitrostyrenes compound in preventing, controlling or resisting plant pathogenic nematodes and preparation thereof 广西田园生化股份有限公司 2025-03-25 CN claimed
CN-119241791-A HTA-BDU-COF polymer and preparation method and application thereof 山东师范大学 2025-01-03 CN claimed
CN-118546440-B High-strength rubber composition for rubber pile and preparation method thereof 河北华密新材科技股份有限公司 2024-12-06 CN claimed
CN-118666272-B Negative electrode material, preparation method thereof and battery 江苏正力新能电池技术股份有限公司 2024-12-03 CN claimed
CN-118844436-A Application of nitrostyrene compound in preventing and treating plant diseases and food-borne pathogenic bacteria 广西田园生化股份有限公司 2024-10-29 CN claimed
CN-115851778-B Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2024-10-01 CN claimed
CN-118666272-A Negative electrode material, preparation method thereof and battery 江苏正力新能电池技术股份有限公司 2024-09-20 CN claimed
EP-0155899-B1 BINDER FOR CHEMICAL AGENTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-01-03 EP claimed
EP-0091383-B1 PROCESS FOR THE CATALYTIC REDUCTION OF NITRO-AROMATIC COMPOUNDS Montedison S.p.A. (IT) 1987-03-04 EP claimed
EP-0094525-B1 GRAFTED RUBBER FOR THE MODIFICATION OF THERMOPLASTIC MOULDING COMPOSITIONS BAYER AG (DE) 1986-12-17 EP claimed
US-4539346-A Binder for chemical agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-09-03 US claimed
US-4481148-A ROCKET PROPELLANT BINDERS, ADHESIVES, SEALS THE B. F. GOODRICH COMPANY (US) 1984-11-06 US claimed
US-4442264-A UNSATURATED AROMATIC NITRO OR CHLORINE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1984-04-10 US claimed
EP-0091383-A1 Process for the catalytic reduction of nitro-aromatic compounds Montedison S.p.A. (IT) 1983-10-12 EP claimed
US-4220804-A EXPLOSIVES, PLASTICIZERS, BINDERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-09-02 US claimed
US-3947492-A Process for producing β-phenyl-γ-amino butyric acid hydrochloride PEREKALIN VSEVOLOD VASILIEVICH 1976-03-30 US claimed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed