Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065912 | 0.89 | MPL (0.49) | MPLLMNAHSD17B10HPGDHIF1A | |
| SCHEMBL10683756 | 0.85 | CYP2D6 (0.44) | MPLLMNAHSD17B10HPGDHIF1A | |
| SCHEMBL8066094 | 0.85 | MPL (0.49) | MPLLMNAHSD17B10HPGDHIF1A | |
| SCHEMBL27999033 | 0.81 | ALDH1A1 (0.56) | LMNAHSD17B10HPGDHIF1ANT5E | |
| SCHEMBL9334347 | 0.79 | NT5E (0.56) | HSD17B10HPGDCTRB1CA2NT5E | |
| SCHEMBL1807925 | 0.79 | MPL (0.51) | MPLESR1ESR2PTGESCTRB1 | |
| SCHEMBL4650562 | 0.78 | MPL (0.50) | MPLLMNAHSD17B10HPGDHIF1A | |
| SCHEMBL4670226 | 0.78 | ESR1 (0.39) | MPLLMNAESR1ESR2PTGES | |
| SCHEMBL9175976 | 0.78 | MPL (0.50) | MPLESR1ESR2PTGESCTRB1 | |
| SCHEMBL11189769 | 0.78 | MPL (0.50) | MPLESR1ESR2PTGESCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102566269-B | Coloured composition, colour filter and display element | JSR株式会社 | 2016-06-15 | — | — | CN | disclosed |