SCHEMBL4650562

SCHEMBL4650562

O=S(=O)(O)c1cc(O)cc2ccc(O)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 3/20 0.50
LMNA P02545 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
PTGES O14684 1/20 0.44
PTGS1 P23219 1/20 0.41
NSD2 O96028 1/20 0.41
MMP14 P50281 1/20 0.41
CASP6 P55212 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
DNMT1 P26358 1/20 0.41
MCL1 Q07820 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 1/20 0.40
CTRC Q99895 1/20 0.40
ABL1 P00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29251544 0.88 MPL (0.50) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL30559736 0.88 MPL (0.50) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL118229 0.85 PTGES (0.52) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL10424165 0.85 ALDH1A1 (0.54) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL18274862 0.85 PTGES (0.52) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL31255685 0.85 PTGES (0.52) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL29364155 0.85 PTGES (0.52) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL31255636 0.85 ALDH1A1 (0.54) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL9845623 0.83 MPL (0.40) MPLLMNAHIF1AHSD17B10HPGD
SCHEMBL12787309 0.83 PTGES (0.55) MPLLMNAHIF1AHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000123-B1 USE OF REACTIVE DYES FOR DYEING HAIR BASF SE (DE) 2008-09-10 EP disclosed
CN-1229099-C Use of reactive dyes for dyeing hair BASF AG (DE) 2005-11-30 CN disclosed
CN-1104472-C Reactive dyes with heterocyclic anchor BASF AG (DE) 2003-04-02 CN disclosed
CN-1104471-C Double reactive dyes BASF AG (DE) 2003-04-02 CN disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
EP-0929610-B1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-08-28 EP disclosed
EP-1027387-B1 DOUBLE REACTIVE DYES DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-02-06 EP disclosed
CN-1072235-C Process for preparing dyed melamine-formaldehyde condensation products BASF AG (DE) 2001-10-03 CN disclosed
EP-1086180-A1 TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 2001-03-28 EP disclosed
US-6197941-B1 TRIAZINE, METALLIZED, AZO, ANTHRAQUINONE, FORMAZAN, PHTHALOCYANINE, AND DIOXAZINE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
EP-0492236-B1 Reactive dyes with alkenylsulphonyl or alkinylsulphonyl groups serving as anchor BASF AG (DE) 1995-08-02 EP disclosed
US-5245020-A Reactive dyes with two or three nitrogen-containing haloheterocycles as reactive system BASF AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
US-5241055-A Use in cold pad-batch processing; fixing; fiber bonding; color- and washfastness; monoazo-, disazo-formazan, triphenyldioxazine and metal phthalocyanine dyes BASF AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
US-5231171-A Dyeing or printing substrates such as cellulose BASF AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5210187-A Cotton or wool, wet fastness BASF AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
US-5149789-A Triazine dyes BASF AKTIENGESELLSCHAFT (DE) 1992-09-22 US disclosed
EP-0492236-A1 Reactive dyes with alkenylsulphonyl or alkinylsulphonyl groups serving as anchor BASF Aktiengesellschaft (DE) 1992-07-01 EP disclosed
US-5003049-A Fiber-Reactive Dyes for Hydroxy Textiles BASF AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
EP-0307817-A1 Double reacting dyes and benzyl sulfonyl intermediates BASF Aktiengesellschaft (DE) 1989-03-22 EP disclosed
US-4677199-A Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals BASF AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed