Quinoline

Quinoline

SCHEMBL28065865

C=Cn1ccnc1C.c1ccc2ncccc2c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
GAA P10253 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HCRTR1 O43613 1/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36575 0.80
Hydrochloric Acid SCHEMBL1007846 0.78
Quinoline SCHEMBL27638019 0.78 ALDH1A1 (0.59) ALDH1A1GAARAB9ANPC1POLB
Quinoline SCHEMBL28194718 0.76 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL8594949 0.74 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL28481300 0.74 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL29349478 0.74 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL28090681 0.74 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL1678429 0.74 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2LMNATDP1RAB9A
Quinoline SCHEMBL29087059 0.72 ALDH1A1 (0.90) ALDH1A1SMN1; SMN2LMNATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459647-B Fast setting aqueous coating 巴斯夫欧洲公司 2019-10-01 CN disclosed
CN-110120541-A Proton-conductive films and fuel cell 丰田自动车株式会社 2019-08-13 CN disclosed
CN-106029750-B Compositions prepared using ionic crosslinkers and methods of making the same 巴斯夫欧洲公司 2019-04-16 CN disclosed
CN-105246932-B Include the composition of copolymer and preparation method thereof of solid grade oligomer and hydrophobic monomer and/or gaseous monomer 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-108291400-A Fire resisting composite pad 巴斯夫欧洲公司 2018-07-17 CN disclosed
CN-107567485-A Barrier compositions 巴斯夫欧洲公司 2018-01-09 CN disclosed
CN-106998678-A Aqueous dispersions of pesticides and polymer particles containing copolymerizable surfactants 巴斯夫欧洲公司 2017-08-01 CN disclosed
CN-104395260-B curable aqueous composition H.B.富勒公司 2017-07-28 CN disclosed
CN-106459647-A Fast setting aqueous coating 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-104321136-B Method for operating a mixing kneader 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-106413397-A Agrochemical suspoemulsions comprising polymer particles prepared from methyl (meth) acrylate and C2-C12 alkyl (meth) acrylates 巴斯夫欧洲公司 2017-02-15 CN disclosed
CN-106061628-A Method for producing multicoat paint systems 巴斯夫涂料有限公司 2016-10-26 CN disclosed
CN-106029750-A Compositions prepared using ionic crosslinkers and methods of making the same 巴斯夫欧洲公司 2016-10-12 CN disclosed
CN-105940031-A Aqueous coating composition and production of multilayer coatings with use of the coating composition 巴斯夫涂料有限公司 2016-09-14 CN disclosed
CN-105848790-A Method for producing multicoat paint systems 巴斯夫涂料有限公司 2016-08-10 CN disclosed
CN-105828961-A Method for producing multicoat paint systems 巴斯夫涂料有限公司 2016-08-03 CN disclosed
CN-105829381-A Aqueous coating composition and preparation of multicoat paint system using said coating composition 巴斯夫涂料有限公司 2016-08-03 CN disclosed
CN-105829462-A Pigment pastes containing an aqueous dispersion of a mixed polymer 巴斯夫涂料有限公司 2016-08-03 CN disclosed
CN-105705016-A A composition comprising an active and a graft copolymer made of N-vinyllactam, vinyl ester, and an alcohol alkoxylate 巴斯夫欧洲公司 2016-06-22 CN disclosed