Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761963 | 0.83 | CTSD (0.64) | BCAT2CTSDGAAHDAC3HDAC4 | |
| SCHEMBL2978269 | 0.81 | CTSD (0.67) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL6766263 | 0.81 | CTSD (0.67) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL28442448 | 0.81 | LMNA (0.58) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL20168851 | 0.81 | CTSD (0.67) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL23358392 | 0.78 | HDAC1 (0.65) | LMNAMAPK1CES2CES1CTSD | |
| SCHEMBL8080269 | 0.78 | HDAC1 (0.65) | LMNAMAPK1CES2CES1CTSD | |
| SCHEMBL4026125 | 0.78 | LMNA (0.65) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL159419 | 0.78 | LMNA (0.65) | LMNAMAPK1BCAT2CES2CES1 | |
| SCHEMBL4136525 | 0.78 | LMNA (0.65) | LMNAMAPK1BCAT2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103981228-B | A kind of lipase-catalyzed benzene glycolylurea is prepared the method for N-carbamyl phenylglycine | JIANG University OF TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | disclosed |