SCHEMBL28065899

SCHEMBL28065899

O=S(=O)(O)c1ccc2cccc(S(=O)(=O)O)c2c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.54
CDK2 P24941 2/20 0.54
FABP4 P15090 1/20 0.54
CCNA2 P20248 1/20 0.54
MAPK14 Q16539 1/20 0.54
NR4A1 P22736 1/20 0.53
CTRB1 P17538 1/20 0.46
CYP1A2 P05177 3/20 0.44
ATIC P31939 2/20 0.42
AURKA O14965 1/20 0.41
AURKB Q96GD4 1/20 0.41
SNCA P37840 2/20 0.40
CHAT P28329 1/20 0.40
MPL P40238 3/20 0.39
CTRC Q99895 2/20 0.39
PHLPP2 Q6ZVD8 1/20 0.39
CD40 P25942 2/20 0.39
CD40LG P29965 2/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13730297 0.87 CDK2 (0.55) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL28757570 0.87 AURKA (0.51) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL9614841 0.84 TTR (0.50) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL1805692 0.84 TTR (0.50) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL7027692 0.84 AURKA (0.53) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL1742117 0.83 TTR (0.59) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL7744816 0.82 TTR (0.51) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL465006 0.80 CDK2 (0.53) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL1755221 0.79 TTR (0.49) TTRCDK2FABP4CCNA2MAPK14
SCHEMBL28211242 0.79 CCNA2 (0.49) TTRCDK2FABP4CCNA2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 CN disclosed