Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065908 | 0.84 | AURKA (0.50) | AURKAAURKBTTRGLO1CTRB1 | |
| SCHEMBL28065899 | 0.84 | TTR (0.54) | AURKAAURKBTTRCTRB1PHLPP2 | |
| SCHEMBL28757570 | 0.82 | AURKA (0.51) | AURKAAURKBTTRCTRB1CYP1A2 | |
| SCHEMBL29360969 | 0.82 | TTR (0.58) | AURKAAURKBTTRGLO1PHLPP2 | |
| SCHEMBL179823 | 0.82 | TTR (0.58) | AURKAAURKBTTRGLO1PHLPP2 | |
| Water SCHEMBL7765550 | 0.80 | TTR (0.56) | AURKAAURKBTTRGLO1PHLPP2 | |
| SCHEMBL21240726 | 0.80 | TTR (0.56) | AURKAAURKBTTRGLO1PHLPP2 | |
| SCHEMBL6472138 | 0.80 | AURKA (0.41) | AURKAAURKBTTRCTRB1CYP1A2 | |
| SCHEMBL2984538 | 0.80 | TTR (0.56) | AURKAAURKBTTRGLO1PHLPP2 | |
| SCHEMBL9614841 | 0.79 | TTR (0.50) | AURKAAURKBTTRGLO1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7076660-A | — | — | None | — | — | JP | disclosed |
| EP-1032613-B1 | REACTIVE DISAZO DYES | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |
| US-6191264-B1 | DYEBASE A CENTRAL 1-HYDROXY-8-AMINONAPHTHALENESULFONIC ACID WITH TERMINAL BENZENE NUCLEI EACH WITH A REACTIVE TRIAZINYLAMINO GROUP, AT LEAST ONE OF WHICH HAS ON THE TRIAZINYL NUCLEUS A CARBAMOYL ALKYLAMINO GROUP | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| JP-H0776660-A | DISAZO REACTIVE DYE | BAYER AG | 1995-03-20 | — | — | JP | disclosed |
| US-5241057-A | Blue shades | BAYER AKTIENGESELLSHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-4839469-A | WET- AND LIGHT-FAST BLUE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-3965087-A | Trisazo dye containing a diphenylenesulfone structure | SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
| US-3951941-A | POLYAZODYE | SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |