Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065899 | 0.84 | TTR (0.54) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL28065857 | 0.83 | TTR (0.47) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL13730297 | 0.82 | CDK2 (0.55) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29360969 | 0.82 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL179823 | 0.82 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29318860 | 0.81 | AURKA (0.46) | TTRNR4A1AURKAAURKBSENP2 | |
| Water SCHEMBL7765550 | 0.80 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21240726 | 0.80 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2984538 | 0.80 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9464970 | 0.79 | CDK2 (0.46) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474654-A1 | WATER SOLUBLE, FIBRE-REACTIVE DYES, PROCESS FOR MANUFACTURING THEM AND THEIR USE. | HOECHST AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |