Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tridecan-1-Ol SCHEMBL28169604 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Myristyl Alcohol SCHEMBL27783736 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Cetostearyl Alcohol SCHEMBL27785964 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Cetyl Alcohol SCHEMBL27940954 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Salicylic Acid SCHEMBL28084608 | 0.93 | ALDH1A1 (0.64) | ALDH1A1KDM4ECA12CA1CA2 | |
| Dodecane SCHEMBL6692297 | 0.93 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 | |
| Salicylic Acid SCHEMBL28366261 | 0.93 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 | |
| Hexadecane SCHEMBL28225619 | 0.93 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 | |
| Salicylic Acid SCHEMBL8621859 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KDM4ECA12CA1CA2 | |
| Cetostearyl Alcohol SCHEMBL27679072 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105581935-A | Pterostilbene submicron lipid particle and preparation method thereof | SHANGHAI KANS COSMETIC CO LTD | 2016-05-18 | — | — | CN | claimed |
| CN-114668685-A | Cosmetic composition capable of strengthening epidermal tight junction to prevent and/or treat atopic dermatitis | NAOS生命科学研究所 | 2022-06-28 | — | — | CN | disclosed |
| CN-113573689-A | Sunscreen compositions comprising butyl methoxydibenzoylmethane, triazine derivatives and light stabilizers | 巴斯夫欧洲公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-109044889-A | Glossy and smooth matte lipstick and production process thereof | 娇时日化（杭州）股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108943922-A | A kind of viscous cross-level double-sided self-adhesive waterproof coiled materials of the red core molecules of TPZ | 韩双 | 2018-12-07 | — | — | CN | disclosed |
| CN-108309819-A | A kind of oil-in-water type suncream of high spf value and preparation method thereof | 佛山云裳化妆品有限公司 | 2018-07-24 | — | — | CN | disclosed |
| CN-106727143-A | A kind of Sin-care composition and CC frosts | 重庆领道科技有限公司 | 2017-05-31 | — | — | CN | disclosed |