Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785547 | 0.87 | HSP90AA1 (0.59) | HSP90AA1HPGDHSP90B1ENPP2HSP90AB1 | |
| SCHEMBL18818608 | 0.81 | DDB1 (0.53) | HSP90AA1DDB1CRBNPOLBHDAC1 | |
| SCHEMBL28410298 | 0.78 | HSP90AA1 (0.41) | HSP90AA1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8207690 | 0.78 | HSP90AA1 (0.43) | HSP90AA1HSP90B1KMT2APOLBRECQL | |
| SCHEMBL17624119 | 0.77 | HSP90AA1 (0.40) | HSP90AA1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL15530492 | 0.76 | HSP90AB1 (0.47) | HSP90AA1HSP90B1KMT2AHDAC1HDAC2 | |
| SCHEMBL21591611 | 0.76 | HSP90AA1 (0.44) | HSP90AA1HPGDHSP90B1ENPP2DDB1 | |
| SCHEMBL28415218 | 0.76 | HSP90AA1 (0.39) | HSP90AA1HSP90B1ENPP2DDB1CRBN | |
| SCHEMBL28422108 | 0.76 | HSP90AA1 (0.32) | HSP90AA1HSP90B1ENPP2DDB1CRBN | |
| SCHEMBL1503877 | 0.76 | MEN1 (0.42) | HSP90AA1HSP90B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | OAT, HAVCR2, CYP3A43 | HSP90AA1 2838/4885HPGD 1569/4885HSD17B10 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.