D-Glutamate

D-Glutamate

SCHEMBL28066265

CC(C)C(N)C(=O)O.CC(C)CC(N)C(=O)O.CC(C)CC(N)C(=O)O.CC(O)C(N)C(=O)O.CC(O)C(N)C(=O)O.NC(CCC(=O)O)C(=O)O.NC(CCC(=O)O)C(=O)O.NC(CO)C(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 4/20 0.47
SLC1A2 P43004 4/20 0.47
SLC1A1 P43005 4/20 0.47
SLC7A5 Q01650 2/20 0.47
GRM8 O00222 2/20 0.47
GRM6 O15303 2/20 0.47
CYP1A2 P05177 2/20 0.47
GRM7 Q14831 2/20 0.47
GRM4 Q14833 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GSR P00390 1/20 0.47
GRIK1 P39086 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
GRIA4 P48058 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL6130151 0.90 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1SLC7A5GRM8
D-Glutamate SCHEMBL27691480 0.89 CYP1A2 (0.60) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL27287949 0.89 CYP1A2 (0.60) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamine SCHEMBL4946782 0.87 ALOX15 (0.47) SLC1A3SLC1A2SLC1A1SLC7A5GRM8
D-Glutamate SCHEMBL23777456 0.86 SLC1A3 (0.53) SLC1A3SLC1A2SLC1A1SLC7A5GRM8
D-Glutamate SCHEMBL27672562 0.86 CYP1A2 (0.53) SLC1A3SLC1A2SLC1A1SLC7A5GRM8
D-Glutamate SCHEMBL27591999 0.86 CYP1A2 (0.53) SLC1A3SLC1A2SLC1A1SLC7A5GRM8
Glutamic Acid SCHEMBL9716073 0.86 CYP1A2 (0.56) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL9716085 0.86 CYP1A2 (0.56) SLC1A3SLC1A2SLC1A1GRM8GRM6
Leucine SCHEMBL26626981 0.84 SLC7A5 (0.67) SLC1A3SLC1A2SLC1A1SLC7A5GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105664149-A Universal vaccine for poly-antigen influenza and preparation method thereof 华东理工大学 2016-06-15 CN disclosed