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Sugi Predict / Compounds / Glutamine

Glutamine

Glutamine

SCHEMBL4946782

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nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.47
▸ BLM P54132 1/20 0.47
▸ PMP22 Q01453 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ SLC1A3 P43003 4/20 0.45
▸ SLC1A2 P43004 4/20 0.45
▸ SLC1A1 P43005 3/20 0.45
▸ SLC7A5 Q01650 2/20 0.45
▸ GRM8 O00222 1/20 0.45
▸ GRM6 O15303 1/20 0.45
▸ GRIN2D O15399 1/20 0.45
▸ GRIN3B O60391 1/20 0.45
▸ GSR P00390 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ GRIK1 P39086 1/20 0.45
▸ GRM5 P41594 1/20 0.45
▸ GRIA1 P42261 1/20 0.45
▸ GRIA2 P42262 1/20 0.45
▸ GRIA3 P42263 1/20 0.45
▸ GRIA4 P48058 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL643795 0.92 ALOX15 (0.56) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL23855677 0.91 ALOX15 (0.58) ALOX15BLMPMP22KMT2ASLC1A3
Glutamic Acid SCHEMBL6130151 0.88 SLC1A3 (0.58) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL642485 0.88 ALOX15 (0.61) ALOX15BLMPMP22KMT2ASLC1A3
D-Glutamate SCHEMBL28066265 0.87 SLC1A3 (0.47) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL16914545 0.87 KMT2A (0.63) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL15017859 0.87 KMT2A (0.63) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL28025692 0.87 KMT2A (0.63) ALOX15BLMPMP22KMT2ASLC1A3
Glutamic Acid SCHEMBL4952416 0.85 SLC1A3 (0.51) ALOX15BLMPMP22KMT2ASLC1A3
Glutamine SCHEMBL8706731 0.85 GSR (0.48) ALOX15BLMPMP22KMT2ASLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1769066-A4 MODIFIED ANTIGEN-PRESENTING CELLS DANA FARBER CANCER INST INC (US) 2008-08-13 — — EP disclosed
EP-1769066-A2 MODIFIED ANTIGEN-PRESENTING CELLS DANA-FARBER CANCER INSTITUTE (US) 2007-04-04 — — EP disclosed
WO-2005113589-A2 MODIFIED ANTIGEN-PRESENTING CELLS DANA-FARBER CANCER INSTITUTE (US) 2005-12-01 — — WO disclosed