SCHEMBL28066537

SCHEMBL28066537

CC1(C(=O)ON)CCC(C(F)(F)F)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.32
FFAR3 O14843 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15536247 0.84 SCN9A (0.33) SCN9AFFAR3
SCHEMBL28167503 0.79 TDP1 (0.32) FFAR3
SCHEMBL27537041 0.78
SCHEMBL6845298 0.77 FFAR3 (0.52) SCN9AFFAR3
SCHEMBL7359222 0.72 FFAR3 (0.42) FFAR3
SCHEMBL17425036 0.72
SCHEMBL1814156 0.71 NPSR1 (0.32) SCN9A
SCHEMBL1814154 0.71 NPSR1 (0.32) SCN9A
SCHEMBL1809492 0.71 NPSR1 (0.32) SCN9A
Hydrochloric Acid SCHEMBL1812449 0.70 NPSR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103649049-B For 3-(biphenyl-3-base)-8,8-two fluoro-hydroxyl-1-azaspiro [4.5]-3-in the last of the ten Heavenly stems alkene-2-ketone being replaced treated and the spirocyclic ketoenols being optionally substituted by halogen 拜耳知识产权有限责任公司 2016-06-29 CN disclosed