Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527879 | 0.98 | ALDH1A1 (0.42) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL17425036 | 0.95 | — | — | |
| SCHEMBL27537041 | 0.92 | — | — | |
| SCHEMBL7739592 | 0.77 | ALDH1A1 (0.45) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL17958 | 0.77 | NPSR1 (0.52) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL1439739 | 0.75 | FFAR3 (0.42) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL17852 | 0.75 | NPSR1 (0.50) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL14445398 | 0.75 | NPSR1 (0.50) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL8527912 | 0.75 | FFAR3 (0.42) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 | |
| SCHEMBL28253114 | 0.75 | FFAR3 (0.42) | FFAR3ALDH1A1SMN1; SMN2NPSR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |